Feasibility and validity of using self-collected capillary blood using Tasso+ for measuring Alzheimer's Disease plasma-based biomarkers among underrepresented populations
While self-collected capillary blood using the Tasso+ device with a 24-hour delay demonstrates high feasibility and excellent validity for measuring GFAP and NfL biomarkers in underrepresented populations, it currently yields unreliable results for Aβ and pTau217 due to hemolysis and processing delays, necessitating optimized pre-analytics before widespread deployment.